Surnames O
- Ober, G & Co. (?-?) – druggist
- Ober, Gustavus (?-?) – druggist
- Ober & Co. – druggist, wholesale
- Ober & McConkey – wholesale druggists
- Obermuller, E. (?-?) – dentist
- O’Brien, Catherine (?-?) – nurse
- O’Brien, Daniel Jerome (1875-1920, Oct. 15) – doctor
- O’Brien, Lucius (?-1841, Jan. 7) – doctor
- O’Bryan, Patrick (?-?) – chemist
- O’Bryne, John (?-?) – chemist
- Ockerman, Sarah S. (?-?) – medical student
- O’Conner, John F. (1791?-1819, Sep. 30) – doctor
- O’Connor, John (1791?-Sep. 30, 1819) – doctor
- O’Conor, Denis F. (?-?) – doctor
- Odel, Daniel (?-?) – nurse
- Odell, Thomas (?-?) – doctor
- O’Donnell, Dominic A. (1790-1874, Aug. 26) – doctor
- O’Donnell, Joseph J. (?-?) – doctor
- O’Donovan, Charles (1829, Sep. 29-1889, Dec. 23) – doctor
- O’Donovan, Charles (1860, Feb. 7-1930, Jan. 24) – doctor
- O’Donovan, John Henry (1867, Oct. 23-?) – doctor
- O’Donovan, John H. D, (1802-1869, Jun. 81) – doctor
- Odorn, Susett (?-?)
- O’Dwyer, [?] (?-?) – doctor
- Oeligrath, Lillan (?-?) – nurse
- Ogburn, Ella B. (?-?) – nurse
- Ogden, Elzabeth (?-?) – nurse, midwife
- Ogle, George Cooke (1816-1890, Nov. 27) – doctor
- Ohle, Henry Charles (1860, Jun. 4-?) – doctor
- Ohlendorf, J. C. (?-?) – druggist
- Ohlendorf, Joseph C. (1862, Sep. 7-?) – doctor
- Ohr, Charles Henry (1811, Oct. 19-?) – doctor
- O’Keefe, Daniel (?-?) – doctor
- O’Keefe, David (?-?) – doctor
- Oldhouser, Minnie (?-?) – nurse
- O’Leary, Charles W. (?-1872, Nov. 13) – doctor
- Oliver, E. S. (?-1902, Mar. 18) – doctor
- Oliver, James L. (?-1865) – doctor
- Oliver, James H. (1811 ca.-1878, Dec. 8) – doctor
- Olsiewska, Clara (?-?) – midwife
- Oman, Thomas B. (?-?) – dentist
- O’Mara, J. T. (?-?) – doctor
- O’Neal, Francis P. (?-?) – doctor
- O’Neal, J. W.C. (?-?) – doctor
- O’Neal, J. L. (?-?) – druggist
- O’Neill, J. W.C. (?-?) – doctor
- O’Neill, Robert J. (?-?) – dentist
- O’Neill, William (?-?) – dentist
- O’Neill & Fischer – druggist — wholesale
- Onnen, Arnold M. (?-?) – apothecary
- Onnen, Charlotte (?-?) – chiropodists
- Onnen, John F. (?-?) – apothecary
- Onnen, Julia A. (?-?) – medical student
- Opie, Eugene L. (1873, Jul. 5-1971, Mar. 12) – doctor
- Opie, Thomas (1840, Feb. 14-1914, Oct. 6) – doctor
- O’Reilly, Robert M. (?-?) – doctor
- Orem, Charles A. (?-?) – druggist
- Orem, Frederick Strattner (?-?) – doctor
- Orem, John (?-?) – apothecary apprentice
- Orrick, George (?-?) – doctor
- Orrick, John Cromwell (1805, Jun. 16-1863, Dec. 29) – doctor
- Orrick, W. O. (?-?) – druggist — wholesale
- Orrick, William (?-?) – druggist, chemist, apothecary
- Orrison, J. Edgar (?-?) – dentist
- Ortel, Henry F. (?-?) – dentist
- Osborn, William H. (?-1881, Jun. 16) – druggist
- Osburn, A. M. (?-?) – doctor
- Osler, William (1849, Jul. 12-1919, Dec. 29) – doctor
- Oswald, John (?-?) – doctor
- O’Toole, Michael F.A. (?-?) – dentist
- Otto, Frederick A. (?-1904, Jan. 16) – druggist
- Otto, George T.W. (?-?) – cupper and leecher
- Otto, Gustavus Carolus (?-?) – doctor
- Otto, John F. (?-?) – apothecary
- Otto, Lellia B. (?-?) – medical student
- Ould, Perry (?-?) – dentist
- Oursler, J. T. (?-?) – pharmacist, USN
- Overton, Louisa (?-?) – midwife
- Owen, Charles W. (?-?) – doctor
- Owen, J. S. (?-?) – doctor
- Owen, John (1775, Sep. 17-1824, Oct.) – doctor
- Owen, Joseph (?-?) – doctor
- Owen, L. J. (?-?) – doctor
- Owen, Mary R. (?-?) – doctor
- Owen, Richard (?-?) – doctor
- Owen, Thomas F. (?-?) – doctor
- Owen-Brill, K. Rose (?-?) – doctor
- Owens, ? (?-?) – doctor
- Owens, [?] (?-?) – doctor
- Owens, Augustus (?-?) – doctor
- Owens, George French (1872, Aug. 12-1925, May 17) – doctor
- Owens, Henry W. (?-?) – doctor
- Owens, Isaac B. (1812-1854) – doctor
- Owens, James S. (ca. 1802-1866, Mar. 5) – doctor
- Owens, John (?-?) – doctor
- Owens, Thomas F. (1821 ca.-1899, Jul. 23) – doctor
- Owens, Thomas (?-?) – doctor
- Owings, A. G. (?-?) – doctor
- Owings, Edward R. (1867, Jul. 2-?) – doctor
- Owings, Harry W. (1837, Sep. 15-1890, Nov. 15) – doctor
- Owings, J. H. (?-?) – doctor
- Owings, James Claggett (1902, Apr. 01-1975, Sep. 25) – doctor
- Owings, James (?-1866) – doctor
- Owings, James L. (?-?) – doctor
- Owings, L. K. (?-?) – doctor
- Owings, Leila (Mrs. E.B. Quillen) (?-?) – nurse
- Owings, Orelliana H. (?-?) – doctor
- Owings, S. Kennedy (?-?) – doctor
- Owings, Samuel B. (?-?) – doctor
- Owings, Thomas F. (?-?) – doctor
- Owings, Thomas Boyle (1830-1914, Aug. 28) – doctor
- Owings, Thomas B. (1802, Dec. 11-1866, Dec. 18) – doctor